Effect of Intramyocardial Injection of Mesenchymal Precursor Cells on Heart Function in People Receiving an LVAD

PHASE2TerminatedINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

August 31, 2009

Primary Completion Date

May 31, 2010

Study Completion Date

February 28, 2011

Conditions
Heart Failure
Interventions
BIOLOGICAL

Mesenchymal Precursor cells (RevascorTM)

Participants will receive intramyocardial injections of low dose (25 million) or higher dose (75 million) MPCs (in sequential cohorts).

DRUG

Cryoprotective media alone

Participants will receive intramyocardial injections of cryoprotective media (placebo).

Trial Locations (17)

10029

Mount Sinai Medical Center, New York

10032

Columbia University Medical Center, New York

10467

Montefiore Medical Center, The Bronx

19104

Hospital of the University of Pennsylvania, Philadelphia

19140

Temple University Hospital, Philadelphia

20010

Washington Hospital Center, Washington D.C.

40202

Jewish Hospital, Louisville

43210

Ohio State University Medical Center, Columbus

48109

University of Michigan, Ann Arbor

53215

St. Luke's Medical Center, Milwaukee

53792

University of Wisconsin, Madison

55455

University of Minnesota, Minneapolis

55902

Mayo Clinic, Rochester

60453

Advocate Christ Medical Center, Oak Lawn

84107

Intermountain Medical Center, Salt Lake City

92123

Sharp Memorial Hospital, San Diego

99204

Sacred Heart Medical Center, Spokane

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

collaborator

Angioblast Systems

INDUSTRY

lead

Icahn School of Medicine at Mount Sinai

OTHER

NCT00927784 - Effect of Intramyocardial Injection of Mesenchymal Precursor Cells on Heart Function in People Receiving an LVAD | Biotech Hunter | Biotech Hunter