Sodium Nitrite in Acute Myocardial Infarction

PHASE2CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

July 31, 2009

Primary Completion Date

June 30, 2016

Study Completion Date

June 30, 2016

Conditions
Acute Myocardial Infarction
Interventions
DRUG

Sodium Nitrite

Subjects assigned to sodium nitrite will receive an initial infusion of 6 nmol/min/kg for 48 hours. After the first six subjects have been enrolled (3 active drug, 3 control) and if there are no dose limiting toxicities, additional cohorts of six subjects each will be randomized to escalating doses of sodium nitrite versus control for a total of 30 subjects.

Trial Locations (3)

21205

Johns Hopkins Bayview Medical Center, Baltimore

21287

Johns Hopkins Hospital, Baltimore

01655

University of Massachusetts Medical School, Worcester

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Hope Pharmaceuticals

INDUSTRY

lead

Johns Hopkins University

OTHER