Prevention Relapse of Graves' Disease by Intrathyroid Injection of Dexamethasone

PHASE4CompletedINTERVENTIONAL
Enrollment

218

Participants

Timeline

Start Date

June 30, 2004

Primary Completion Date

December 31, 2008

Study Completion Date

March 31, 2009

Conditions
Graves' Disease
Interventions
DRUG

MMI combined with IID

MMI titration regimen for 18 months,initial dosage of MMI was 20 mg/d,which combined with IID for 3 months.Dexamethasone was injected into the two side of thyroid, the dose of dexamethasone was 5 mg by every side, twice a week. The treatment strategy was changed to once a week at the second month and twice a month at the third month, the dose of dexamethasone was the same as the first month.

DRUG

MMI

MMI treatment with titration regimen for 18 months, initial dosage was 20 mg/d.

All Listed Sponsors
lead

Xiao-Ming Mao

OTHER

NCT00917241 - Prevention Relapse of Graves' Disease by Intrathyroid Injection of Dexamethasone | Biotech Hunter | Biotech Hunter