217
Participants
Start Date
October 31, 2004
Primary Completion Date
April 30, 2008
Study Completion Date
April 30, 2008
Cerebrolysin + donepezil
"Cerebrolysin (10 ml) was given as IV infusion on five days per week for four consecutive weeks (week 1-4) with repetition of this treatment course (week 13-16) after a two-months treatment free interval, accounting for a total of 40 infusions.~Donepezil was given PO once daily during the whole study duration (28 weeks). After four weeks the daily dosage was increased from 5 mg to 10 mg."
Cerebrolysin + placebo
"Cerebrolysin (10 ml) was given as IV infusion on five days per week for four consecutive weeks (week 1-4) with repetition of this treatment course (week 13-16) after a two-months treatment free interval, accounting for a total of 40 infusions.~Placebo for donepezil was given PO once daily during the whole study duration (28 weeks)."
Donepezil + placebo
"Placebo for Cerebrolysin was given as IV infusion on five days per week for four consecutive weeks (week 1-4) with repetition of this treatment course (week 13-16) after a two-months treatment free interval, accounting for a total of 40 infusions.~Donepezil was given PO once daily during the whole study duration (28 weeks). After four weeks the daily dosage was increased from 5 mg to 10 mg."
EuroEspes Biomedical Research Centre, A Coruña
Centro Geriátrico Fuente Salinas, Granada
Clínica de Memoria, Málaga
Lead Sponsor
acromion GmbH
INDUSTRY
Ever Neuro Pharma GmbH
INDUSTRY