Impact of Fluticasone and Salmeterol on Airway Dendritic Cells (DCs) in Smokers

PHASE1CompletedINTERVENTIONAL
Enrollment

45

Participants

Timeline

Start Date

May 31, 2009

Primary Completion Date

October 31, 2009

Study Completion Date

December 31, 2009

Conditions
Smoke-related Lung DiseasesChronic Obstructive Pulmonary Disease
Interventions
DRUG

fluticasone

Participants inhale fluticasone (250 µg) via discus. Before and after this therapy, a bronchoalveolar lavage is performed.

DRUG

fluticasone/salmeterol

Participants inhale fluticasone/salmeterol (250/50µg) via discus. Before and after this therapy, a bronchoalveolar lavage is performed.

DRUG

placebo

Participants inhale placebo twice daily via discus. Before and after this therapy, a bronchoalveolar lavage is performed.

Trial Locations (1)

18057

Dep. of Pneumology, University of Rostock, Rostock

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

GlaxoSmithKline

INDUSTRY

lead

University of Rostock

OTHER

NCT00908362 - Impact of Fluticasone and Salmeterol on Airway Dendritic Cells (DCs) in Smokers | Biotech Hunter | Biotech Hunter