Neuradiab® Combined With Bevacizumab (Avastin) Therapy in Patients With Recurrent Glioblastoma Multiforme

PHASE2UnknownINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

May 31, 2009

Primary Completion Date

September 30, 2010

Study Completion Date

December 31, 2010

Conditions
Brain Tumors
Interventions
DRUG

Neuradiab in combination with Bevacizumab (Avastin)

"Patients will be treated following surgical removal of recurrent glioblastoma with a single intracavitary dose of Neuradiab® delivering 44 Gy±10% to the ridge of the surgically created resection cavity followed by therapy with Bevacizumab (Avastin) at a minimum of 30 days after Neuradiab administration.~Treatment with Bevacizumab will consist of 10mg/kg iv on days 1 and 15 every 28 days. Other chemotherapies (in addition to Avastin) will be permitted based on most current clinical practice and clinical evaluation of the patient."

Trial Locations (1)

27710

The Preston Robert Tisch Brain Tumor Center, Durham

Sponsors
All Listed Sponsors
lead

Bradmer Pharmaceuticals Inc.

INDUSTRY

NCT00906516 - Neuradiab® Combined With Bevacizumab (Avastin) Therapy in Patients With Recurrent Glioblastoma Multiforme | Biotech Hunter | Biotech Hunter