Safety Trial of Single Versus Multiple Dose Thymoglobulin Induction in Kidney Transplantation

PHASE2CompletedINTERVENTIONAL
Enrollment

99

Participants

Timeline

Start Date

March 31, 2010

Primary Completion Date

July 31, 2014

Study Completion Date

July 31, 2014

Conditions
End-Stage Renal DiseaseKidney Failure
Interventions
BIOLOGICAL

Single-dose rabbit Anti-thymocyte Globulin induction

6 mg of rATG administered in a single dose on the day of kidney transplantation

BIOLOGICAL

Divided-dose rabbit Anti-thymocyte Globulin induction

6 mg/kg total rabbit Anti-thymocyte Globulin dose administered as 1.5 mg/kg doses on 4 sequential days, beginning on the day of kidney transplantation.

Trial Locations (4)

27157

Wake Forest University, Winston-Salem

68198

University of Nebraska Medical Center, Omaha

77030

The Methodist Hospital Research Institute, Houston

85724

University of Arizona, Tucson

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Sanofi

INDUSTRY

collaborator

University of Arizona

OTHER

collaborator

Wake Forest University

OTHER

collaborator

University of Nebraska

OTHER

collaborator

The Methodist Hospital Research Institute

OTHER

lead

Wright State University

OTHER