An Open Label Study of the Effects of Eculizumab in Neuromyelitis Optica

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

14

Participants

Timeline

Start Date

April 30, 2009

Primary Completion Date

December 31, 2011

Study Completion Date

December 31, 2011

Conditions
Neuromyelitis OpticaDevic's Disease
Interventions
DRUG

Eculizumab

"The patient will receive eculizumab at a dose of 600mg intravenously (an infusion given into the vein) each week for 4 weeks, then 900mg intravenously at the fifth week, then 900mg every 2 weeks for 48 weeks.~The first infusion will be given at Mayo Clinic site; subsequent infusions will be administered in the subject's home by a company which will send a nurse to administer the infusion. Subjects will receive therapy for a total of 12 months."

Trial Locations (2)

55905

Mayo Clinic, Rochester

85259

Mayo Clinic, Scottsdale

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Alexion Pharmaceuticals, Inc.

INDUSTRY

lead

Mayo Clinic

OTHER