Abraxane and RT for Non-Small Cell Lung Cancer (NSCLC)

PHASE2WithdrawnINTERVENTIONAL
0
Timeline

Start Date

March 31, 2008

Primary Completion Date

March 31, 2012

Conditions
Non-small Cell Lung Cancer, Stage III
Interventions
RADIATION

radiation therapy

1\) PTV = CTV (GTV + 1.5-cm margins and the most adjacent nodal regions) + 0.5 cm margins to 5,040 cGy in 180 cGy daily fractions; and (2) Cone Down PTV = GTV +1.5 cm margins to 6,480 cGy.

DRUG

Paclitaxel Protein-Bound, and CARBOPLATIN

Induction Chemotherapy Abraxane(260 mg/m2) / Carboplatin (AUC of 6) x one cycle Concurrent Chemotherapy(with radiation)--for first 3 pts--20 mg/m2 Abraxane, 3 times per week then for next group of 3 pts--30 mg/m2 Abraxane twice a week

Trial Locations (1)

14642

University of Rochester, Medical Center, Rochester

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Celgene Corporation

INDUSTRY

lead

University of Rochester

OTHER