4,000
Participants
Start Date
December 31, 2003
Primary Completion Date
January 31, 2025
Study Completion Date
January 31, 2025
comparative genomic hybridization
Collection of sputum, blood, urine, and a small amount of lung tissue.
gene expression microarray analysis
Collection of sputum, blood, urine, and a small amount of lung tissue.
proteomic profiling analysis
Collection of sputum, blood, urine, and a small amount of lung tissue.
biologic sample preservation procedure
Collection of sputum, blood, urine, and a small amount of lung tissue.
nasal brushing
Using a brush, superficial cells are removed from the nose.
Blood draw
Venous blood will be collected
Urine collection
Subjects will be asked to provide a urine specimen.
sputum sample
Prior to their bronchoscopy, subjects will be asked for a sputum specimen. This is a collection of mucous that you cough up.
fluorescence bronchoscopy with airway biopsy
A flexible tube attached to a fluorescent light source will be inserted into the subject's mouth or nose to reach the airway. Samples of the lining of the airway will be taken, as well as bronchial secretions and epithelial cell from brushings of the lining of the airway.
fine needle aspiration of the lung
A small needle is inserted into the lung to collect tissue. This procedure will only be performed if the patient's physician orders it.
thoracentesis
A small needle is inserted into the patient's lung cavity and a small amount of fluid is collected. This procedure will only be performed if the patient's physician orders it.
RECRUITING
Vanderbilt-Ingram Cancer Center, Nashville
RECRUITING
Veterans Affairs Medical Center - Nashville, Nashville
National Cancer Institute (NCI)
NIH
Vanderbilt-Ingram Cancer Center
OTHER