NCT00889863 - Flare Prevention Study of Canakinumab in Patients With Active Systemic Juvenile Idiopathic Arthritis (SJIA) | Biotech Hunter

Enrollment

177

Participants

Timeline

Start Date

July 31, 2009

Primary Completion Date

September 30, 2011

Study Completion Date

September 30, 2011

Conditions

Systemic Juvenile Idiopathic Arthritis With Active Flare

Interventions

DRUG

canakinumab

Canakinumab 4 mg/kg dose subcutaneous injection supplied as 6 mL glass vials each containing 150 mg canakinumab as a lyophilized cake.

DRUG

placebo

Placebo powder matching canakinumab supplied as 6 mL glass vials containing a lyophilized cake for subcutaneous injection every 4 weeks in Part II.

Trial Locations (73)

20010

Children's National Medical Center, Washington D.C.

40202

University of Louisville, Louisville

45229

Children's Hospital Medical Center, Cincinnati

Children's Hospital/Neurology, Cincinnati

60637

University of Chicago Medical Center, Chicago

72202

Arkansas Children's Hospital Research Inst, Little Rock

78723

Specially For Children, Austin

97227

Legacy Emanuel Hospital, Portland

97232

Legacy Emanual Research, Portland

02111

New England Medical Center - Department of Allergy, Boston

Tufts Medical Center, Boston

07039

St Barnabas Ambulatory Care Center, Livingston

Unknown

Novartis Investigative Site, Buenos Aires

Novartis Investigative Site, Capital Federal

Novartis Investigative Site, La Plata

Novartis Investigative site, Brussels

Novartis Investigative site, Ghent

Novartis Investigative Site, Laken

Novartis Investigative site, Leuven

Novartis Investigative Site, Curitiba

Novartis Investigative site, Porto Alegre

Novartis Investigative site, Rio de Janiero

Novartis Investigative site, São Paulo

Novartis Investigative site, Vancouver

Novartis Investigative site, Halifax

Novartis Investigative site, Toronto

Novartis Investigative site, Montreal

Novartis Investigative Site, Le Kremlin-Bicêtre

Novartis Investigative Site, Lyon

Novartis Investigative Site, Paris

Novartis Investigative Site, Strasbourg

Novartis Investigative Site, Bad Bamstedt

Novartis Investigative site, Berlin

Novartis Investigative Site, Bremen

Novartis Investigative Site, Freiburg im Breisgau

Novartis Investigative Site, Geißen

Novartis Investigative Site, Hamburg

Novartis Investigative Site, Münster

Novartis Investigative Site, Saint Augustin

Novartis Investigative Site, Stuttgart

Novartis Investigative Site, Budapest

Novartis Investigative Site, Haifa

Novartis Investigative Site, Kfar Saba

Novartis Investigative Site, Petah Tikva

Novartis Investigative Site, Ramat Gan

Novartis Investigative Site, Rehovot

Novartis Investigative Site, Bologna

Novartis Investigative Site, Florence

Novartis Investigative Site, Genova

Novartis Investigative site, Milan

Novartis Investigative site, Napoli

Novartis Investigative site, Padua

Novartis Investigative site, Rome

Novartis Investigative site, Scafati

Novartis Investigative site, Torino

Novartis Investigative site, Utrecht

Novartis Investigative Site, Oslo

Novartis Investigative Site, Lima

Novartis Investigative site, Warsaw

Novartis Investigative site, Berea

Novartis Investigative site, Mayville

Novartis Investigative site, Johannesburg

Novartis Investigative site, Pretoria

Novartis Investigative site, Barcelona

Novartis Investigative site, Madrid

Novartis Investigative site, Valencia

Novartis Investigative site, Stockholm

Novartis Investigative Site, Bern

Novartis Investigative site, Lausanne

Novartis Investigative site, Zurich

Novartis Investigative site, Ankara

Novartis Investigative Site, Istanbul

Novartis Investigative Site, Izmir