41
Participants
Start Date
July 31, 2009
Primary Completion Date
March 31, 2012
Study Completion Date
March 31, 2012
ABT-263
150 mg of ABT-263 is taken orally once daily on Days 1-5 or Days 1-3 of each 21 day cycle. 150 mg of ABT-263 on Days 1-3, 8-10 and 15-17 of each 28-day cycle. This is a dose escalation study, therefore the dose of ABT-263 will change throughout the study.
Docetaxel
75 mg/m2 will be given by intravenous infusion on day 1 of each 21 -day cycle. 30 mg/m2 will be given by intravenous infusion on day 1, 8, 15 of each 28 -day cycle.
Site Reference ID/Investigator# 43962, Baltimore
Site Reference ID/Investigator# 44182, Fort Lauderdale
Site Reference ID/Investigator# 51982, Scottsdale
Site Reference ID/Investigator# 12844, Rotterdam
Site Reference ID/Investigator# 20042, Rotterdam
Site Reference ID/Investigator# 12845, Surrey
Lead Sponsor
Collaborators (1)
Genentech, Inc.
INDUSTRY
Abbott
INDUSTRY