Extending the Time for Thrombolysis in Emergency Neurological Deficits

PHASE3CompletedINTERVENTIONAL
Enrollment

180

Participants

Timeline

Start Date

June 30, 2010

Primary Completion Date

August 27, 2018

Study Completion Date

August 27, 2018

Conditions
Stroke
Interventions
DRUG

Tissue Plasminogen Activator (Alteplase)

0.9 mg/kg up to a maximum of 90mg, intravenous, 10% as bolus and the remainder over 1 hour

DRUG

Placebo

placebo provided as 50mg lyophilised powder to be reconstituted with sterile water in glass vials indistinguishable from active drug

Trial Locations (22)

1001

Auckland Hospital, Auckland

2065

Royal North Shore Hospital, St Leonards

2145

Westmead Hospital, Westmead

2259

Gosford Hospital, Kanwal

3011

Western Hospital, Footscray

3050

Royal Melbourne Hospital, Melbourne

3121

Epworth Healthcare, Richmond

3128

Box Hill Hospital, Box Hill

3168

Monash Medical Centre, Clayton

3220

Geelong Hospital, Geelong

4029

Royal Brisbane & Women's Hospital, Brisbane

4560

Sunshine Coast University Hospital, Nambour

5000

Royal Adelaide Hospital, Adelaide

5042

Flinders Medical Centre, Bedford Park

5112

Lyell McEwin Hospital, Elizabeth Vale

6000

Royal Perth Hospital, Perth

6009

St. Vincent's Hospital, Sydney

Sir Charles Gairdner Hospital, Nedlands

Unknown

John Hunter Hospital, Newcastle

Gold Coast University Hospital, Gold Coast

Austin Hospital, Heidelberg

Helsinki University Central Hospital, Helsinki

Sponsors
All Listed Sponsors
collaborator

Commonwealth Scientific and Industrial Research Organisation, Australia

OTHER_GOV

collaborator

University of Melbourne

OTHER

collaborator

Melbourne Health

OTHER

collaborator

The Florey Institute of Neuroscience and Mental Health

OTHER

lead

Neuroscience Trials Australia

OTHER

NCT00887328 - Extending the Time for Thrombolysis in Emergency Neurological Deficits | Biotech Hunter | Biotech Hunter