NCT00886769 - Single-dose Study to Assess Efficacy of Canakinumab (ACZ885) in Patients With Active Juvenile Idiopathic Arthritis (SJIA) | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

July 31, 2009

Primary Completion Date

December 31, 2010

Study Completion Date

January 31, 2011

Conditions

Systemic Juvenile Idiopathic Arthritis

Interventions

DRUG

Canakinumab

Canakinumab was supplied in individual 6 mL glass vials each containing 150 mg canakinumab powder as a lyophilized cake. Each reconstituted vial provided 150mg of canakinumab per 1 mL.

DRUG

Placebo

Placebo was provided in individual 6 mL glass vials each containing 150 mg placebo powder matching canakinumab as a lyophilized cake. Each reconstitued vial provided 150mg of placebo per 1 mL.

Trial Locations (91)

20010

Children's National Medical Center, Washington D.C.

35233

University of Alabama at Birmingham, Birmingham

40202

University of Louisville, Louisville

43205

Nationwide Children's Hospital, Columbus

45229

Children's Hospital Medical Center, Cincinnati

Children's Hospital/Neurology, Cinncinati

60637

University of Chicago Medical Center, Chicago

72202

Arkansas Children's Hospital Research Inst, Little Rock

78723

Specially For Children, Austin

90027

Children's Hospital Los Angeles, Los Angeles

97227

Legacy Emanuel Hospital, Portland

97232

Legacy Emanual Research, Portland

02111

Tufts Medical Center, Boston

Tufts New England Medical Center-Dept. of Allergy, Boston

07039

St. Barnabas Ambulatory Care Center, Livingston

Unknown

Novartis Investigative Site, Buenos Aires

Novartis Investigative Site, Capital Federal

Novartis Investigative Site, La Plata

Novartis Investigative site, Brussels

Novartis Investigative site, Ghent

Novartis Investigative Site, Laken

Novartis Investigative site, Leuven

Novartis Investigative Site, Curitiba

Novartis Investigative site, Porto Alegre

Novartis Investigative site, Rio de Janeiro

Novartis Investigative site, São Paulo

Novartis Investigative site, Vancouver

Novartis Investigative site, Halifax

Novartis Investigative site, Toronto

Novartis Investigative site, Montreal

Novartis Investigative site, Calgary

Novartis Investigative site, Arhus N

Novartis Investigative Site, Le Kremlin-Bicêtre

Novartis Investigative Site, Lyon

Novartis Investigative Site, Paris

Novartis Investigative Site, Strasbourg

Novartis Investigative Site, Bad Bamstedt

Novartis Investigative site, Berlin

Novartis Investigative Site, Bremen

Novartis Investigative site, Dresden

Novartis Investigative Site, Freiburg im Breisgau

Novartis Investigative site, Garmisch-Partenkirch

Novartis Investigative Site, Geißen

Novartis Investigative Site, Hamburg

Novartis Investigative site, Hanover

Novartis Investigative site, Krefeld

Novartis Investigative site, Mainz

Novartis Investigative Site, Münster

Novartis Investigative Site, Saint Augustin

Novartis Investigative Site, Stuttgart

Novartis Investigative site, Tübingen

Novartis Investigative site, Thessaloniki

Novartis Investigative Site, Budapest

Novartis Investigative Site, Haifa

Novartis Investigative Site, Kfar Saba

Novartis Investigative Site, Petah Tikva

Novartis Investigative Site, Ramat Gan

Novartis Investigative Site, Rehovot

Novartis Investigative Site, Bologna

Novartis Investigative Site, Florence

Novartis Investigative Site, Genova

Novartis Investigative site, Milan

Novartis Investigative site, Napoli

Novartis Investigative site, Padua

Novartis Investigative site, Rome

Novartis Investigative site, Scafati

Novartis Investigative site, Torino

Novartis Investigative site, Utrecht

Novartis Investigative Site, Oslo

Novartis Investigative Site, Lima

Novartis Investigative site, Warsaw

Novartis Investigative site, Berea

Novartis Investigative site, Mayville

Novartis Investigative site, Pretoria

Novartis Investigative site, Barcelona

Novartis Investigative site, Madrid

Novartis Investigative site, Valencia

Novartis Investigative site, Stockholm

Novartis Investigative Site, Bern

Novartis Investigative site, Lausanne

Novartis Investigative site, Zurich

Novartis Investigative site, Ankara

Novartis Investigative Site, Istanbul

Novartis Investigative Site, Izmir

Novartis Investigative site, Birmingham

Novartis Investigative site, Liverpool

Novartis Investigative site, London

Novartis Investigative site, Manchester

Novartis Investigative site, New Castle Upon Tyne

Novartis Investigative site, Norwich

Novartis Investigative site, Oxford