A Study Evaluating the Safety of ABT-263 in Combination With Etoposide/Cisplatin in Subjects With Cancer

PHASE1CompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

October 31, 2009

Primary Completion Date

July 31, 2011

Study Completion Date

July 31, 2011

Conditions
Solid Tumors
Interventions
DRUG

ABT-263

150mg of ABT-263 is taken daily for 3 out of 21 days. This is a dose escalation study, therefore the dose of ABT-263 will change throughout the study.

DRUG

etoposide/cisplatin

etoposide = 100 mg/m2 Days 1-3 of each Cycle; Max duration 6 cycles. cisplatin = 75 mg/m2 Day 1 of each Cycle; Max duration 6 cycles

Trial Locations (7)

21231

Site Reference ID/Investigator# 12303, Baltimore

48202

Site Reference ID/Investigator# 43505, Detroit

60153

Site Reference ID/Investigator# 12841, Maywood

60637

Site Reference ID/Investigator# 13323, Chicago

02215

Site Reference ID/Investigator# 12305, Boston

Site Reference ID/Investigator# 20381, Boston

08901

Site Reference ID/Investigator# 13322, New Brunswick

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Genentech, Inc.

INDUSTRY

lead

AbbVie (prior sponsor, Abbott)

INDUSTRY