NCT00877227View on ClinicalTrials.gov

Does B Vitamin Supplementation Decrease Homocysteine Concentrations in Newborns

PHASE1CompletedINTERVENTIONAL
Enrollment

37

Participants

Timeline

Start Date

January 31, 2003

Primary Completion Date

November 30, 2003

Study Completion Date

November 30, 2003

Conditions
Mild Hyperhomocysteinemia
Interventions
DRUG

5-formyltetrahydrofolate (10 mg/ml) (Pharmachemie bv)

Folinic acid was given for two weeks as 5-formyltetrahydrofolate (10 mg/ml) (Pharmachemie bv). This solution was administered either intravenously (first week) or orally. To lower homocysteine in adults 5 mg/day folic acid is frequently used. Using an average bodyweight of 70 kg for adults we calculated a daily dose of 70 microgram/kg/day for our newborns.

Trial Locations (1)

6500HB

Radboud University Medical center Nijmegen, Nijmegen

All Listed Sponsors
lead

Radboud University Medical Center

OTHER

NCT00877227 - Does B Vitamin Supplementation Decrease Homocysteine Concentrations in Newborns | Biotech Hunter | Biotech Hunter