S-1 and Photodynamic Therapy in Cholangiocarcinoma

PHASE3CompletedINTERVENTIONAL
Enrollment

43

Participants

Timeline

Start Date

February 28, 2009

Primary Completion Date

July 31, 2013

Study Completion Date

August 31, 2013

Conditions
Cholangiocarcinoma
Interventions
DRUG

S-1 Chemotherapy

S-1 chemotherapy before intolerable complication or definite tumor progression Based on the body surface area, \<1.25m2: 80mg/day, 1.25\~1.5m2: 100mg/day, ≧1.5m2: 120mg/day Given orally twice daily for 14days, followed by 7 days without treatment

PROCEDURE

Photodynamic therapy

PDT with Photofrin® 2mg/kg i.v. 48hrs before laser activation

PROCEDURE

Systemic chemotherapy except S-1

Variable systemic chemotherapy except S-1

Trial Locations (1)

138-736

Asan Medical Center, Seoul

Sponsors
All Listed Sponsors
lead

Asan Medical Center

OTHER