Ixabepilone and Cyclophosphamide as Neoadjuvant Therapy in HER-2 Negative Breast Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

168

Participants

Timeline

Start Date

April 30, 2009

Primary Completion Date

July 31, 2014

Study Completion Date

October 31, 2014

Conditions
Breast Cancer
Interventions
DRUG

Ixabepilone

40 mg/m2 IV infusion over 3 hours on day 1 of a 21 day cycle for 6 cycles

DRUG

Cyclophosphamide

600 mg/m2 IV infusion per institutional guidelines on day 1 of a 21 day cycle for 6 cycles

Trial Locations (20)

20817

Center for Cancer and Blood Disorders, Bethesda

National Capital Clinical Research Consortium, Bethesda

23235

Virginia Cancer Institute, Richmond

29210

South Carolina Oncology Associates, PA, Columbia

30501

Northeast Georgia Medical Center, Gainesville

30901

Medical Oncology Associates of Augusta, Augusta

33180

Aventura Medical Center, Aventura

33805

Watson Clinic Center for Cancer Care and Research, Lakeland

33901

Florida Cancer Specialists, Fort Myers

37203

Tennessee Oncology, Nashville

37404

Chattanooga Oncology Hematology Associates, Chattanooga

38017

Family Cancer Center, Collierville

45242

Oncology Hematology Care, Cincinnati

47802

Providence Medical Group, Terre Haute

63017

St. Louis Cancer Care, Chesterfield

68114

Methodist Cancer Center, Omaha

73505

Cancer Centers of Southwest Oklahoma, Lawton

78258

South Texas Oncology and Hematology, San Antonio

04101

Mercy Hospital, Portland

07960

Hematology Oncology Associates of Northern NJ, Morristown

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Bristol-Myers Squibb

INDUSTRY

lead

SCRI Development Innovations, LLC

OTHER