Bringing Simple Urge Incontinence Diagnosis & Treatment to Providers (BRIDGES)

PHASE4CompletedINTERVENTIONAL
Enrollment

645

Participants

Timeline

Start Date

January 31, 2009

Primary Completion Date

May 31, 2010

Study Completion Date

May 31, 2011

Conditions
Urge Urinary IncontinenceOveractive Bladder
Interventions
DRUG

Fesoterodine

Participants will be instructed to take one tablet of blinded study medication once a day, orally, for 12 weeks. They will start with a 4 mg dose of study medication and will have the option of doubling that dose after 2 or 4 weeks if they wish. At the end of the 12 week blinded trial, participants will be offered open-label fesoterodine (Toviaz™), for 9 months beginning at 4 mg with participant directed dose adjustment.

DRUG

Matching Placebo

Participants will be instructed to take one tablet of blinded study medication once a day, orally, for 12 weeks. They will start with a 4 mg dose of study medication and will have the option of doubling that dose after 2 or 4 weeks if they wish. At the end of the 12 week blinded trial, participants will be offered open-label fesoterodine (Toviaz™), for 9 months beginning at 4 mg with participant directed dose adjustment.

Trial Locations (13)

15213

University of Pittsburgh, Pittsburgh

19104

University of Pennsylvania Medical Center, Philadelphia

22908

University of Virginia-Women's Midlife Health Center, Charlottesville

35233

University of Alabama at Birmingham, Birmingham

38120

University of Tennessee Health Science Center, Memphis

48109

University of Michigan, Ann Arbor

52242

University of Iowa Hospitals and Clinics, Iowa City

78229

University of Texas Health Science Center San Antonio, San Antonio

87131

University of New Mexico Health Sciences Center, Albuquerque

92093

University of California San Diego, San Diego

94115

University of California, San Francisco, San Francisco

97239

Oregon Health and Science University, Portland

02903

Women & Infants' Hospital, Division of Urogynecology, Providence

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Pfizer

INDUSTRY

lead

University of California, San Francisco

OTHER