In-Situ Therapeutic Cancer Vaccine for Metastatic Cancer Combining AlloStim With Tumor Cryoablation

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

August 31, 2009

Primary Completion Date

March 31, 2011

Study Completion Date

May 31, 2011

Conditions
Metastatic Cancer
Interventions
BIOLOGICAL

AlloStim-7

intradermal injection once a week for 3 weeks

PROCEDURE

percutaneous tumor cryoablation

ablation of a tumor by percutaneous cryoablation under CT guidance

BIOLOGICAL

AlloStim-7

intratumoral injection into cryoablated tumor lesion 1 hour after ablation

BIOLOGICAL

AlloStim8 or AlloStim-9

intravenous infusion of AlloStim one week following ablation procedure. First cohort to receive 10\^8 cell dose and if no toxicity dose escalates to 10\^9 cell dose.

Trial Locations (1)

92010

Immunovative Clinical Research, Inc, Carlsbad

Sponsors
All Listed Sponsors
lead

Mirror Biologics, Inc.

INDUSTRY

NCT00861107 - In-Situ Therapeutic Cancer Vaccine for Metastatic Cancer Combining AlloStim With Tumor Cryoablation | Biotech Hunter | Biotech Hunter