55
Participants
Start Date
June 30, 2009
Primary Completion Date
February 10, 2022
Study Completion Date
May 31, 2026
177Lu-J591
177Lu-J591 70 mCi/m2 on day 29 (+/- 2 days) of treatment
Ketoconazole
Ketoconazole at a dose of 400 mg (two 200 mg tabs) to be taken orally (preferably on an empty stomach) three times per day (total daily dose of 1200 mg)
Hydrocortisone
Hydrocortisone at a dose of 20 mg orally each morning, 10 mg orally each evening (total daily dose of 30 mg)
111In-J591
111In-J591 at a dose of 5 mCi on day 29 (+/- 2 days) of treatment
Weill Cornell Medical College, New York
UPMC Hillman Cancer Center, Pittsburgh
Georgetown University Medical Center, Washington D.C.
Indiana University Melvin and Bren Simon Cancer Center, Indianapolis
University of Iowa Hospitals and Clinics, Iowa City
The University of Kansas Cancer Center, Westwood
University of Utah, Salt Lake City
Cedars Sinai, Los Angeles
USC/Norris Comprehensive cancer center, Los Angeles
United States Department of Defense
FED
Weill Medical College of Cornell University
OTHER