Evaluation of the Pharmacokinetics of NRL972 Following Pre-Administration of Rifampicin and Cyclosporine

PHASE1CompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

June 30, 2006

Primary Completion Date

July 31, 2006

Study Completion Date

August 31, 2006

Conditions
Pharmacokinetics
Interventions
DRUG

NRL972

Single intravenous administration of 2 mg NRL972 after pre-treatment with 600 mg p.o. rifampicin once daily from the evening of Day D-7 until the evening of Day D-1

DRUG

NRL972

Reference test: Single intravenous administration of 2 mg NRL972

DRUG

NRL972

Single intravenous administration of 2 mg NRL972 injection after pre-treatment with 100 mg cyclosporine on the evening of Day D-1 and on the morning of Day D01 one hour before administration of NRL972

Trial Locations (1)

1527

"Dept. Clinical Pharmacology & Therapeutics, MHAPT Zaritza Johanna University Hospital", Sofia

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Norgine

INDUSTRY

NCT00856752 - Evaluation of the Pharmacokinetics of NRL972 Following Pre-Administration of Rifampicin and Cyclosporine | Biotech Hunter | Biotech Hunter