An Exploratory, Randomized, Blinded, Placebo-Controlled Trial of Folic Acid and L-methylfolate in Parkinson's Disease

NATerminatedINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

December 31, 2006

Primary Completion Date

June 30, 2010

Study Completion Date

June 30, 2010

Conditions
Parkinson's Disease
Interventions
DIETARY_SUPPLEMENT

Folic Acid, Vitamin B6, Vitamin B12

"Intervention #1. A combination of the following vitamin supplements: 2.5mg of folate, 25mg of vitamin B6 and 2mg of vitamin B12. This combination will be described as triple therapy with folate."

DIETARY_SUPPLEMENT

B6, B12, L-methylfolate

Intervention #2. A combination of the following vitamin supplements: 2.8mg of L-methylfolate, 25 mg of vitamin B6 and 2mg of vitamin B12.

DIETARY_SUPPLEMENT

B6, B12, Placebo

"Intervention #3. A combination of the following vitamin supplements: 25mg of vitamin B6 and 2mg of vitamin B12 without supplementary folate or L-methylfolate. This combination will be described as triple therapy with placebo"

Trial Locations (1)

11030

The Feinstein Institute For Medical Recearch, Manhasset

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Northwell Health

OTHER

NCT00853879 - An Exploratory, Randomized, Blinded, Placebo-Controlled Trial of Folic Acid and L-methylfolate in Parkinson's Disease | Biotech Hunter | Biotech Hunter