Atacicept in Multiple Sclerosis Extension Study, Phase II

PHASE2TerminatedINTERVENTIONAL
Enrollment

74

Participants

Timeline

Start Date

March 31, 2009

Primary Completion Date

September 30, 2009

Study Completion Date

February 28, 2011

Conditions
Relapsing Multiple Sclerosis
Interventions
DRUG

Atacicept 25 mg

Subjects who received atacicept 25 milligram (mg) subcutaneously (SC) as loading dose twice weekly for first 4 weeks, followed by atacicept 25 mg SC for 32 weeks, in 28063 study will continue with atacicept 25 mg SC once weekly up to 5 years or up to early termination of treatment or early termination of the study.

DRUG

Atacicept 75 mg

Subjects who received atacicept 75 mg SC as loading dose twice weekly for first 4 weeks, followed by atacicept 75 mg SC for 32 weeks, in 28063 study will continued with atacicept 75 mg SC once weekly up to 5 years or up to early termination of treatment or early termination of the study.

DRUG

Atacicept 150 mg

Subjects who received atacicept 150 mg SC as loading dose twice weekly for first 4 weeks, followed by atacicept 150 mg SC for 32 weeks, in 28063 study will continue with atacicept 150 mg SC once weekly up to 5 years or up to early termination of treatment or early termination of the study.

DRUG

Atacicept 150 mg

Subjects who received placebo SC twice weekly for first 4 weeks, followed by placebo SC for 32 weeks, in 28063 study will continue with atacicept 150 mg (without loading dose) SC once weekly up to 5 years or up to early termination of treatment or early termination of the study.

Trial Locations (47)

Unknown

Research Site, Phoenix

Research Site, Northbrook

Research Site, East Lansing

Research Site, Cleveland

Research Site, Philadelphia

Research Site, Nashville

Research Site, Box Hill VIC

Research Site, Fitzroy

Research Site, New Lambton

Research Site, Woodville

Research Site, Diepenbeek

Research Site, Sijsele

Research Site, Calgary

Research Site, Ottawa

Research Site, Brno

Research Site, Hradec Králové

Research Site, Caen

Research Site, Saint-Herblain

Research Site, Bochum

Research Site, Düsseldorf

Research Site, Beirut

Research Site, Kaunas

Research Site, Breda

Research Site, Nieuwegein

Research Site, Rotterdam

Research Site, Winston Salem

Research Site, Moscow

Research Site, Novosibirsk

Research Site, Saint Petersburg

Research Site, Samara

Research Site, Vladimir

Research Site, Yaroslavl

Research Site, Yekaterinburg

Research Site, Barcelona

Research Site, Madrid

Research Site, Málaga

Research Site, Stockholm

Research Site, Basel

Research Site, Innsbruck

Research Site, Zurich

Research Site, Kharkiv

Research Site, Kyiv

Research Site, Odesa

Research Site, Uzhhorod

Research Site, London

Research Site, Sheffield

Research Site, Stoke-on-Trent

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Merck KGaA, Darmstadt, Germany

INDUSTRY

lead

EMD Serono

INDUSTRY

NCT00853762 - Atacicept in Multiple Sclerosis Extension Study, Phase II | Biotech Hunter | Biotech Hunter