NCT00850577 - Ph II of a Novel Anti-angiogenic Agent in Combination With Chemotherapy for the Treatment of Non-Small Cell Lung Cancer | Biotech Hunter

Enrollment

255

Participants

Timeline

Start Date

June 30, 2009

Primary Completion Date

August 31, 2013

Study Completion Date

August 31, 2013

Conditions

Non-small Cell Lung Cancer (NSCLC)

Interventions

DRUG

Paclitaxel

Solution, IV, 200 mg/m2, Q21days, 6 cycles

DRUG

Carboplatin

Solution, IV, AUC=6, Q21days, 6 cycles

DRUG

CT-322

Solution, IV, 2 mg/kg, Q7days, Until PD

DRUG

Bevacizumab

Solution, IV, 15 mg/kg, Q21days, Until PD

DRUG

Bevacizumab placebo (ie saline solution)

Solution, IV, 0 mg/kg, On days 8 and 15 of a 3-weekly cycle, Until PD

Trial Locations (55)

6045

Local Institution, Port Elizabeth

7570

Local Institution, Cape Town

7700

Local Institution, Rondebosch

7925

Local Institution, Cape Town

13915

Local Institution, Marseille

18840

Guthrie Clinic, Ltd, Sayre

21401

Annapolis Oncology Center, Annapolis

21740

Meritus Center For Clinical Research, Hagerstown

24073

Blue Ridge Cancer Care, Christiansburg

27103

Piedmont Hematology Oncology Associates, Pllc, Winston-Salem

29414

Charleston Hematology Oncology Associates, Pa, Charleston

31059

Local Institution, Toulouse

32804

Cancer Institute Of Florida, Orlando

33401

Palm Beach Cancer Institute, West Palm Beach

35033

Local Institution, Rennes

37044

Local Institution, Tours

38104

University Of Tennessee Cancer Institute, Memphis

38501

Cancer Center At Cookeville Regional Medical Center, Cookeville

38801

North Mississippi Hematology And Oncology Associates, Ltd, Tupelo

41701

Kentucky Cancer Clinic, Hazard

44710

North Canton Medical Clinic Center, Canton

47014

Local Institution, Meldola (Fc)

47900

Local Institution, Rimini

48100

Local Institution, Ravenna

60077

Clintell, Inc., Skokie

67214

Cancer Center Of Kansas, Wichita

75005

Local Institution, Paris

80952

Local Institution, Gdansk

85715

Acrc/Arizona Clinical Research Center, Inc., Tucson

92123

Sharp Clinical Oncology Research, San Diego

97227

Kaiser Permanente Oncology/Hematology, Portland

98503

Providence Western Washington Oncology, Lacey

115478

Local Institution, Moscow

143423

Local Institution, Moscow

153013

Local institution, Ivanovo

454087

Local Institution, Chelyabinsk

60336550

Local Institution, Fortaleza

02903

Rhode Island Hospital, Providence

30130-100

Local Institution, Belo Horizonte

20231-050

Local Institution, Rio de Janeiro

90050-170

Local Institution, Porto Alegre

14784-400

Local Institution, Barretos

04024-002

Local Institution, São Paulo

05403-000

Local Institution, São Paulo

00189

Local Institution, Roma

05100

Local Institution, Terni

15-540

Local Institution, Bialystok

05-400

Local Institution, Otwock

60 569

Local Institution, Poznan

70-891

Local Institution, Szczecin

02-781

Local Institution, Warsaw

115 478

Local Institution, Moscow

0002

Local Institution, Pretoria

M23 9LT

Local Institution, Manchester

LS9 7TF

Local Institution, Leeds