429
Participants
Start Date
June 30, 2009
Primary Completion Date
April 30, 2013
Study Completion Date
April 30, 2013
Phase 1: Etanercept
Phase 1: prefilled syringe 50mg/ml, administered once weekly for study weeks 0 - 24
Phase 1: Methotrexate
Phase 1: oral tablet, 2.5mg, dose variable from 7.5mg to 25mg, once weekly for study weeks 0 - 24.
Phase 2: Optional ETN, SSZ, HCQ, MTX
"Phase 2: All therapies are optional and may include any combination of the following: ETN, SSZ, HCQ, MTX Phase 2: Optional ETN: prefilled syringe 50mg/ml, dose variable after study week 24 to week 128.~Phase 2: Optional SSZ: oral tablet, 0.5gm, dose variable per approved local label recommendations after study week 24 to week 128.~Phase 2: HCQ: oral tablet, 200mg, dose variable per approved local label recommendations after study week 24 to week 128.~Phase 2: MTX: oral tablet, 2.5mg dose variable after week 24 to week 128."
Phase 1: Methotrexate
Phase 1: oral tablet, 2.5mg dose variable from 7.5mg to 25mg, once weekly for study weeks 0 - 24.
Phase 1: Conventiaonal DMARD
Phase 1: SSZ: oral tablet, 0.5gm, dose variable per approved local label recommendations. OR Phase 1: HCQ: oral tablet, 200mg, dose variable per approved local label recommendations.
OMI, Buenos Aires
Centro de Investigaciones en Enfermedades Reumaticas, Buenos Aires
Hospital Britanico, Buenos Aires
Atencion Integral en Reumatologia, Buenos Aires
Hospital Escuela Gral. San Martin, Corrientes
Centro de Investigaciones Reumatologicas, San Miguel de Tucumán
Centro Medico Privado de Reumatologia, San Miguel de Tucumán
Sanatorio Mayo, Córdoba
CER San Juan, San Juan
Centro de Investigación y Biomedicina de Chihuahua, Chihuahua City
Hospital Christus Mugerza, Chihuahua City
Hospital Christus Muguerza del Parque, Chihuahua City
Hospital Angeles Chapalita, Guadajara
Investigaciones Reumatológicas y Osteológicas, Buenos Aires
Consultorios Especializados en Investigaciones Medicas, Capital Federal
Instituto CAICI, Rosario
Centro de Osteopatías Médicas, Buenos Aires
Dr Miranda Private Practice, Santiago
Hospital del Salvador, Santiago
Reumalab, Medellín
Centro de Reumatologia y Ortopedia, Barranquilla
IPS Centro Integral de Rematología del Caribe S.A.S CIRCARIBE S.A.S Sede 1, Barranquilla
IPS Centro Integral de Rematología del Caribe S.A.S CIRCARIBE S.A.S Sede 2, Barranquilla
Foqus Ips Ltda, Bogota
Fundacion Instituto de Reumatologia Fernando Chalem, Bogota
Riesgo de fractura S.A. Clinica de Artritis y Rehabilitacion, Bogota
Preventive Care Ltda, Chía
Centro Medico Carlos Ardila Lulle, Bucaramanga
Servimed EU, Bucaramanga
Centro de Especialidades Medicas del Sureste SA de CV, Mérida
Centro de Infusion Marbella, Panama City
Centro de Investigacion Marbella, Panama City
Centro Integral de Reumatologia e Inmunologia LTDA, Bogota