Safety Study of Lenalidomide Maintenance Therapy Post Allogeneic HCT for High-risk Multiple Myeloma

PHASE2CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

February 28, 2009

Primary Completion Date

January 31, 2013

Study Completion Date

March 31, 2014

Conditions
Multiple Myeloma
Interventions
DRUG

lenalidomide

"Lenalidomide maintenance therapy will start within 60 to 90 days after allogeneic HCT at a starting dose of 10mg PO once daily.~Dose escalation and de-escalation are performed depending on tolerability of lenalidomide.~The dose range is 5mg every other day and 5 to 25 mg daily from days 1-21 followed by 7 days of rest for 12 cycles (each cycle 28 days)."

Trial Locations (8)

19104

University of Pennsylvania Hospital Center, Philadelphia

33612

H. Lee Moffitt Cancer Center & Research Institute, Tampa

53226

Medical College of Wisconsin, Milwaukee

55455

University of Minnesota Medical Center, Minneapolis

77030

The University of Texas, M.D. Anderson Cancer Center, Houston

91010

City of Hope National Medical Center, Duarte

98195

Fred Hutchinson Cancer Research Center, Seattle

07601

Hackensack University Medical Center, Hackensack

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

National Marrow Donor Program

OTHER

collaborator

Celgene Corporation

INDUSTRY

lead

Center for International Blood and Marrow Transplant Research

NETWORK