Gemcitabine, Cisplatin, and Sunitinib (GC-S) as Neoadjuvant Chemotherapy in Patients With Muscle-Invasive Bladder Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

February 28, 2009

Primary Completion Date

November 30, 2012

Study Completion Date

November 30, 2012

Conditions
Bladder CancerUrinary Bladder
Interventions
DRUG

Sunitinib

Sunitinib will be administered at a dose of 25mg orally once daily for 2 consecutive weeks followed by a 1 week rest period.

DRUG

Gemcitabine

Gemcitabine 1,000 mg/m\^2

DRUG

cisplatin

cisplatin 35 mg/m\^2 will be administered intravenously on days 1 and 8.

Trial Locations (5)

10065

Memorial Sloan-Kettering Cancer Center, New York

11570

Memorial Sloan-Kettering Cancer Center at Mercy Medical Center, Rockville Centre

11725

Memorial Sloan-Kettering Cancer Center @ Suffolk, Commack

07920

Memorial Sloan-Kettering at Basking Ridge, Basking Ridge

Unknown

Memoral Sloan Kettering Cancer Center@Phelps, Sleepy Hollow

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Pfizer

INDUSTRY

lead

Memorial Sloan Kettering Cancer Center

OTHER