The Role of Nitric Oxide Synthase Isoforms in the Cardiovascular Effects of Air Pollution

NACompletedINTERVENTIONAL
Enrollment

16

Participants

Timeline

Start Date

April 30, 2012

Primary Completion Date

June 30, 2013

Study Completion Date

June 30, 2013

Conditions
Endothelial Dysfunction
Interventions
PROCEDURE

Forearm vascular study

Forearm venous occlusion plethysmography to measure forearm blood flow during intrabrachial infusion of nitric oxide synthase inhibitors L-NMMA (2-8 µg/min), S-methionyl-L-citrulline (25-200 nmol/min) and 1400W (100-1000 nmol/min) and positive control norepinephrine (60-540 pmol/min)

Trial Locations (1)

Unknown

Umeå University, Umeå

All Listed Sponsors
collaborator

NHS Lothian

OTHER_GOV

collaborator

Umeå University

OTHER

lead

University of Edinburgh

OTHER

NCT00845169 - The Role of Nitric Oxide Synthase Isoforms in the Cardiovascular Effects of Air Pollution | Biotech Hunter | Biotech Hunter