Effect of Maraviroc on Endothelial Function in HIV-Infected Patients

PHASE3CompletedINTERVENTIONAL
Enrollment

52

Participants

Timeline

Start Date

January 31, 2010

Primary Completion Date

December 31, 2012

Study Completion Date

June 30, 2014

Conditions
HIV InfectionCardiovascular DiseaseInflammationHIV Infections
Interventions
DRUG

Maraviroc

For subjects assigned to the maraviroc group, they will receive maraviroc at 300mg by mouth twice daily for 24 weeks in addition to taking their current anti-HIV medications. For subjects on ritonavir, the dose will be reduced to 150mg by mouth twice daily for 24 weeks.

DRUG

placebo

For subjects assigned to the placebo group, they will receive a matching placebo pill 300mg to be taken by mouth twice daily for 24 weeks in addition to taking their current anti-HIV medications.

Trial Locations (1)

94110

University of California, San Francisco, San Francisco

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

collaborator

Pfizer

INDUSTRY

lead

University of California, San Francisco

OTHER