Study of Cicletanine for Pulmonary Arterial Hypertension (PAH)

PHASE2TerminatedINTERVENTIONAL
Enrollment

162

Participants

Timeline

Start Date

January 31, 2009

Primary Completion Date

October 31, 2011

Study Completion Date

March 31, 2012

Conditions
Pulmonary Arterial Hypertension
Interventions
DRUG

Cicletanine

Cicletanine capsules 150 mg or 300 mg administered orally once or twice daily

DRUG

Cicletanine Placebo

Placebo to match cicletanine administered orally once daily, followed by active cicletanine in the blinded extension period

Trial Locations (56)

1070

ULB Hôpital Erasme, Brussels

1090

University Klinik Wien, Vienna

2010

St Vincent's Hospital, Darlinghurst

6001

Royal Perth Hospital, Perth

8036

University Klinik Graz, Graz

H Clinic i Provincial, Barcelona

10003

Beth Israel Medical Center, New York

10021

Cornell University, New York

10029

Mount Sinai Medical Center, New York

10032

New York Presbyterian Hospital, New York

14623

University of Rochester, Rochester

15212

Allegheny General Hospital, Pittsburgh

15213

University of Pittsburgh Medical Center, Pittsburgh

19104

University of Pennsylvania, Philadelphia

21201

University of Maryland, Baltimore

22908

University Of Virginia, Charlottesville

27599

University of North Carolina at Chapel Hill, Chapel Hill

28041

HU 12 de Octubre, Madrid

30322

Emory University, Atlanta

30912

Medical College of Georgia, Augusta

32610

University of Florida, Gainesville

33331

Cleveland Clinic, Fort Lauderdale

35392

Universitaetsklinikum Giessen und Marburg, Giessen

36617

University of South Alabama, Mobile

44106

Case Medical Center, Cleveland

45219

The Lindner Clinical Trial Center, Cincinnati

49100

Rabin Medical Center, Petah Tikva

52242

University of Iowa, Iowa City

52621

Chaim Sheba Medical Center, Ramat Gan

55905

Mayo Clinic, Rochester

60637

University of Chicago Hospital, Chicago

63110

Washington University School of Medicine, St Louis

64718

Unidad de Investigación Clínica en Medicina S.C., Monterrey

70112

Louisiana State University, New Orleans

75390

University of Texas Southwestern Medical Center at Dallas, Dallas

77030

Baylor College of Medicine, Houston

80045

University of Colorado Denver, Aurora

80336

Ludwig-Maximilians-Universitaet, Munich

84157

Intermountain Medical Center, Murray

85013

Arizona Pulmonary Specialists, Phoenix

90073

VA Greater LA Healthcare System, Los Angeles

90502

UCLA Medical Center, Torrance

92037

University of California San Diego Medical Center, San Diego

95124

Harish H. K. Murthy, MD, San Jose

06030

University of Connecticut Health Center, Farmington

02111

Tufts-New England Medical Center, Boston

02114

Massachusetts General Hospital, Boston

02115

Children's Hospital Boston, Boston

02118

Boston University School of Medicine, Boston

43210-1252

Davis Heart and Lung Research Institute, Columbus

02903

Rhode Island Hospital, Providence

T1Y6J4

Peter Lougheed Centre, Calgary

N6A5W9

London Health Sciences Centre, London

H3T1E2

Jewish General Hospital, Montreal

Unknown

Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City

NW32QG

Royal Free Hospital, London

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Gilead Sciences

INDUSTRY