A Study to Evaluate Safety, Tolerability, Plasma Drug Levels, and Cognitive Response Following Multiple Doses of a Drug in Healthy Elderly Participants.

PHASE1CompletedINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

January 31, 2009

Primary Completion Date

May 31, 2009

Study Completion Date

May 31, 2009

Conditions
HealthyElderly
Interventions
DRUG

PF-04447943

Planned oral dose is PF-04447943, 5 mg q12 hours for 7 days.

DRUG

PF-04447943

Planned oral dose is PF-04447943, 15 mg q12 hours for 7 days.

DRUG

PF-04447943

Planned oral dose is PF-04447943, 35 mg q12 hours for 7 days. Actual dose may be adjusted based on pharmacokinetic and other data from prior dose cohorts.

DRUG

PF-04447943

Planned oral dose is PF-04447943, 35 mg q12 hours for 7 days. Actual dose may be adjusted based on pharmacokinetic and other data from prior dose cohorts.

DRUG

PF-04447943

Planned oral dose is PF-04447943, 35 mg q12 hours for 14 days. Actual dose may be adjusted downward based on pharmacokinetic and other data from prior dose cohorts.

Trial Locations (1)

32608

Pfizer Investigational Site, Gainesville

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY