Study to Evaluate the Efficacy and Safety of Temozolomide in Subjects With Brain Metastases of Either Malignant Melanoma, Breast, or Non-small Cell Lung Cancer (P02064)

PHASE2CompletedINTERVENTIONAL
Enrollment

162

Participants

Timeline

Start Date

December 1, 2000

Primary Completion Date

October 20, 2006

Study Completion Date

October 20, 2006

Conditions
Metastases of Central Nervous SystemMelanomaBreast NeoplasmCarcinoma, Non-Small-Cell Lung
Interventions
DRUG

Temozolomide

150 mg/m2 given once a day for 7 consecutive days (Days 1 through 7) repeated every other week until disease progression or toxicity or for a maximum of one year. After amendment, schedule was modified: a second rest week was added after the second wash-out week (Days 1 through 7, 15 through 21 every 35).

All Listed Sponsors
collaborator

Quintiles, Inc.

INDUSTRY

lead

Merck Sharp & Dohme LLC

INDUSTRY

NCT00831545 - Study to Evaluate the Efficacy and Safety of Temozolomide in Subjects With Brain Metastases of Either Malignant Melanoma, Breast, or Non-small Cell Lung Cancer (P02064) | Biotech Hunter | Biotech Hunter