Dimebon (PF-01913539)-Digoxin Drug-Drug Interaction Study In Healthy Subjects

PHASE1CompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

February 28, 2009

Primary Completion Date

May 31, 2009

Study Completion Date

May 31, 2009

Conditions
Alzheimer DiseaseHuntington Disease
Interventions
DRUG

digoxin

digoxin once daily (0.125 mg QD) plus placebo three times daily (TID), 8 hours apart for 14 days.

DRUG

digoxin

digoxin once daily (0.125 mg QD) for 14 days.

DRUG

dimebon

Dimebon three times a day, 8 hours apart for 14 days (10 mg TID on Days 1-7 and 20 mg TID on Days 8-14).

Trial Locations (1)

06511

Pfizer Investigational Site, New Haven

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Medivation, Inc.

INDUSTRY

lead

Pfizer

INDUSTRY