Neoadjuvant Weekly Ixabepilone for High Risk, Clinically Localized Prostate Cancer

Ixabepilone, 16 mg/m2 or 20mg/m2, weekly x 3, in 4 week cycles, x 4 cycles.

Prostatectomy 2-8 weeks after completion \*\*\*this was standard of care and not a part of the study\*\*