An Open-Label Study of QD Oral Administration of Tivozanib (AV-951) in Subjects With Non-Small Cell Lung Cancer (NSCLC)

PHASE1CompletedINTERVENTIONAL
Enrollment

17

Participants

Timeline

Start Date

January 31, 2009

Primary Completion Date

March 31, 2011

Study Completion Date

May 31, 2011

Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
DRUG

Tivozanib (AV-951)

"Subjects will receive 1.0 or 1.5 mg tivozanib (AV-951) once daily continuously beginning on Day 1 for 4 weeks. One cycle will be defined as 4 weeks of treatment. Cycles will be repeated every 4 weeks in the absence of disease progression or unacceptable toxicity.~Minimum of 8 weeks (2 consecutive dosing cycles), if tolerated."

Trial Locations (3)

10021

Memorial Sloan-Kettering, New York

20007

Georgetown University, Washington D.C.

66160

Kansas University Medical Center, Kansas City

Sponsors
All Listed Sponsors
lead

AVEO Pharmaceuticals, Inc.

INDUSTRY