6
Participants
Start Date
February 28, 2009
Primary Completion Date
February 28, 2013
Study Completion Date
April 30, 2014
Trastuzumab
IV at 2 mg/kg over 30 minutes on day 1 of each weekly cycle. Patients who have not received trastuzumab for 4 weeks or more will receive a loading dose of 4 mg/kg over 90 minutes day 1 of the first cycle. The dose of trastuzumab will be based on the patient's actual weight at the start of each 4 week treatment cycle.
PF03512676
Patients also receive PF03512676 subcutaneously on days 15 and 22 of course 1 and on days 1, 8, 15, and 22 of all subsequent courses.
Correlative Studies
Blood for performing the correlative studies will be drawn on week 1, 2, 6, 12 and 18.
The Ohio State University Wexner Medical Center, Columbus
Collaborators (1)
Pfizer
INDUSTRY
Bhuvaneswari Ramaswamy
OTHER