A Pilot Study of Eicosapentaenoic Acid (EPA) in Patients With Cancer Cachexia

NACompletedINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

July 31, 2007

Primary Completion Date

March 31, 2010

Study Completion Date

August 31, 2010

Conditions
Cancer Cachexia
Interventions
DRUG

Eicosapentaenoic Acid

Participants will receive Lovaza at a dose of 4 g for 6 weeks. Participants will be examined at six weeks for change in protein status as indicated by change in morphological (Height, weight, body mass index, body composition, lean body mass, body fat %), and biochemical (serum prealbumin) markers of protein status and immunological cytokines (Il-6, TNF- α) markers implicated in cancer cachexia. At baseline, 3 and 6 weeks, participants will undergo interviews and laboratory analysis for determining compliance and treatment-related toxicity.

Trial Locations (2)

33612

H. Lee Moffitt Cancer Center & Research Institute, Tampa

34997

Martin Memorial, Stuart

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

GlaxoSmithKline

INDUSTRY

lead

H. Lee Moffitt Cancer Center and Research Institute

OTHER