24
Participants
Start Date
December 31, 2008
Primary Completion Date
September 30, 2014
Study Completion Date
September 30, 2014
Fludarabine
40 mg/m\^2 by vein over 60 minutes on Day -5 through Day -2.
Busulfan
Busulfan administered at the dose calculated to achieve an area under curve (AUC) of 4000 µMol-min + 12% based on the pharmacokinetic studies (days -5, -4, -3, and -2).
Thymoglobulin
2.5 mg/kg by vein over about 4-6 hours on Day -3 through Day -1.
Azacitidine
Start cycles of 32 mg/m\^2 daily as an injection under the skin once a day over 5 days in a row, starting about 5 weeks after the transplant. This may be repeated once a month for up to 4 months after the transplant.
Stem Cell Transplant
Stem cell infusion on day 0 administered by vein after collected from donor.
University of Texas MD Anderson Cancer Center, Houston
Collaborators (1)
National Cancer Institute (NCI)
NIH
Celgene Corporation
INDUSTRY
M.D. Anderson Cancer Center
OTHER