127
Participants
Start Date
January 31, 2001
Primary Completion Date
July 31, 2005
Study Completion Date
July 31, 2005
Sirolimus
Loading dose 30 mg for three days, trough level of 10-20 ng/ml month 1-3, 8-15 ng/ml month 4 - 6
Cyclosporine A
Loading dose of 300 mg for three days, trough levels 250-300 ng/ml months 1-3, 150-250 ng/ml months 4 to 6
Prednisone
0.5 mg/kg, tapering every two weeks until 0.1 mg/kg
Mycophenolate mofetil
2 x 1000mg, through level above 2ug/ml
Protocol biopsies
protocol kidney biopsies at month one and three
University Hospital Basel, Clinic for Transplantation Immunology and Nephrology, Basel
Wyeth is now a wholly owned subsidiary of Pfizer
INDUSTRY
University Hospital, Basel, Switzerland
OTHER