Study of Subcutaneous Campath-1H in Patients With B-Cell CLL and Residual Disease After Chemotherapy

PHASE2UnknownINTERVENTIONAL
Enrollment

31

Participants

Timeline

Start Date

December 31, 2003

Primary Completion Date

August 31, 2010

Study Completion Date

August 31, 2010

Conditions
B-Cell Chronic Lymphocytic Leukemia
Interventions
BIOLOGICAL

Alemtuzumab (Campath-1H)

Campath is administered using escalating doses and alternating injection sites. The dose is escalated as tolerated using 3mg,10mg,and 30mg, administered subcutaneously (SC) (if tolerated). When escalation to 30 mg dose is tolerated, all subsequent doses are administered at 30 mg SC 3 times per week at alternating injection sites for up to 8 weeks

Trial Locations (3)

92093

University of California San Diego, La Jolla

02115

Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute, Boston

77030-4009

M. D. Anderson Cancer Center at University of Texas, Houston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Bayer

INDUSTRY

lead

Chronic Lymphocytic Leukemia Research Consortium

NETWORK