Vaccination of Patients With Ovarian Cancer With Dendritic Cell/Tumor Fusions With Granulocyte Macrophage Colony-stimulating Factor (GM-CSF) and Imiquimod

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

23

Participants

Timeline

Start Date

August 31, 2008

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2024

Conditions
Ovarian CancerPrimary Peritoneal CancerFallopian Tube Cancer
Interventions
DRUG

GM-CSF

Injections given subcutaneously at the sight of vaccination on the day of the vaccination and for three days afterwards

BIOLOGICAL

Dendritic Cell/Tumor Fusion Vaccine

Given subcutaneously once every three weeks for a total of three vaccines

DRUG

imiquimod

Cream applied to the skin at the injection sight 2 hours before injection and for 3 days following the injection

Trial Locations (4)

02114

Massachusetts General Hospital, Boston

02115

Brigham & Women's Hospital, Boston

Dana-Farber Cancer Institute, Boston

02215

Beth Israel Deaconess Medical Center, Boston

All Listed Sponsors
collaborator

Dana-Farber Cancer Institute

OTHER

collaborator

Brigham and Women's Hospital

OTHER

collaborator

Massachusetts General Hospital

OTHER

collaborator

National Cancer Institute (NCI)

NIH

lead

Beth Israel Deaconess Medical Center

OTHER