NCT00798655 - Trial of Postoperative Radiation, Cisplatin, and Panitumumab in Locally Advanced Head and Neck Cancer | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

November 30, 2007

Primary Completion Date

June 30, 2015

Study Completion Date

November 9, 2016

Conditions

Cancer of HeadCancer of Head and NeckCancer of NeckCancer of the HeadCancer of the Head and NeckCancer of the NeckHead and Neck CancerHead CancerHead NeoplasmsHead, Neck NeoplasmsNeck CancerNeck NeoplasmsNeoplasms, HeadNeoplasms, Head and NeckNeoplasms, NeckNeoplasms, Upper Aerodigestive TractUADT NeoplasmsUpper Aerodigestive Tract Neoplasms

Interventions

DRUG

Panitumumab

"Panitumumab, starting dose, 2.5mg/kg will be given as an intravenous infusion (IV) through a vein in your arm, once a week before radiation and chemotherapy for 6 weeks; treatment takes about an hour.~The panitumumab dose will be calculated based on the subject's actual weekly body weight"

DRUG

Cisplatin

Cisplatin, 30 mg/m2 will be given as an intravenous infusion (IV) through a vein in your arm, once a week before radiation therapy and after panitumumab for 6 weeks; treatment takes about an hour

RADIATION

Radiation Therapy

"Radiation Therapy 60-66 Gy/200 cGy/daily, five days a week, Monday through Friday, except on weekends and holidays, for six weeks; treatments take about 20 minutes.~Radiation will be administered either prior to chemo treatment or after chemo treatment as long as radiation is given on the same day."

Trial Locations (1)

15232

University of Pittsburgh Cancer Institute, Pittsburgh