Short Neoadjuvant Hemithoracic IMRT for MPM

PHASE1/PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

October 31, 2008

Primary Completion Date

September 30, 2027

Study Completion Date

September 30, 2027

Conditions
Malignant Pleural Mesothelioma
Interventions
OTHER

Pre-op RT +/- chemotherapy

Patients on the study will receive IMRT for approximately 1 week of 5 daily treatments. Short pre-operative hemithoracic RT is a new technique. 1 week post-RT, they will proceed with an extrapleural pneumonectomy. If the mediastinal lymph nodes that are removed during surgery are positive for tumour cells, 3 cycles of chemotherapy, consisting of raltitrexed and cisplatin, will be given 6-12 weeks post-surgery.

Trial Locations (1)

M5G 2M9

University Health Network, Toronto

All Listed Sponsors
lead

University Health Network, Toronto

OTHER

NCT00797719 - Short Neoadjuvant Hemithoracic IMRT for MPM | Biotech Hunter | Biotech Hunter