274
Participants
Start Date
June 30, 2002
Primary Completion Date
February 28, 2006
Study Completion Date
February 28, 2006
Nadroparin
LMWH is given with a weight adjusted dose of 86 international anti-factor Xa units of nadroparin (Fraxiparine) per kilogram of body weight(86 anti-factor Xa IU/kg) subcutaneously every 12 hours,which will be used at least 5-7 days.
Unfractionated heparin(UFH)
UFH is received with an initial bolus dose of 80 IU per kilogram, followed by a continuous intravenous infusion at an initial rate of 18 IU per kilogram per hour. The dose is subsequently adjusted so that the activated partial thromboplastin time (APTT) would be 1.5 to 2.5 times the control value in normal subjects. The tests are performed 4 hours after the start of treatment, whenever a sub-therapeutic APTT had been measured after a dose adjustment, and otherwise daily.UFH will be used at least 5-7 days.
Peking University First Hospital, Beijing
Beijing General Hospital of the Air-force PLA, Beijing
Beijing Naval General Hospital, Beijing
Peking University People's Hospital, Beijing
Beijing Friendship Hospital, Capital Medical University, Beijing
Beijing No 6 Hospital, Beijing
Peking University Third Hospital, Beijing
Beijing Hospital, Beijing
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing
The First Hospital of China Medical University, Shenyang
The General Hospital of Shenyang Military Command, Shenyang
The Affiliated Hospital of Shenyang Medical University, Shenyang
Liaoning Angang Tiedong Hospital, Anshan
Shanghai Ruijin Hospital, Shanghai
Shanghai Changhai Hospital, Shanghai
Shanghai Pulmonary Hospital(8), Shanghai
Qilu Hospital Affiliated to Shandong University, Jinan
Shandong Yantaishan Hospital, Yantai
The Affiliated Hospital of Medical College Qingdao, Qingdao
The Affiliated Hospital of Medical College Jining, Jining
Tianjin Thoracic Hospital, Tianjin
Tianjin Medical University General Hospital, Tianjin
Sir Run Run Shaw Hospital, Affiliated with Zhejiang University, Hangzhou
The First Affiliated Hospital of Wenzhou Medical College, Wenzhou
Wuhan Union Hospital, Wuhan
The First Affiliated Hospital of Zhengzhou University, Zhengzhou
The First Affiliated Hospital Sun Yat-Sen University, Guangzhou
Guangzhou Institute of Respiratory Disease，Guangzhou Medical University, Guangzhou
The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou
Shenzhen People's Hospital, Shenzhen
The First Affiliated Hospital of Guangxi Medical University, Nanning
The Affiliated Hospital of Ningxia Medical University, Yinchuan
Xinjiang People's Hospital, Ürümqi
The Second Affiliated Hospital of Hebei Medical University, Shijiazhuang
Tangshan Worker's Hospital, Hebei Medical University, Tangshan
The Affiliated Hospital of Hubei Coal University, Tangshan
Shanxi Datong 5th Hospital, Datong
The First Affiliated Hospital of Shanxi Medical University, Taiyuan
The Second Affiliated Hospital of Shanxi Medical University, Taiyuan
Beijing Chao Yang Hospital
OTHER