Multiple Dose Study In Cancer Patients: Safety and Tolerability of BMS-754807 in Combination With Paclitaxel and Carboplatin in Patients With Advanced or Metastatic Solid Tumors

PHASE1CompletedINTERVENTIONAL
Enrollment

21

Participants

Timeline

Start Date

April 30, 2009

Primary Completion Date

June 30, 2012

Study Completion Date

June 30, 2012

Conditions
Advanced Solid TumorsMetastatic Solid Tumors
Interventions
DRUG

BMS-754807

Tablets, Oral, escalating doses starting at 10 mg, continuous or intermittent, until disease progression, unacceptable toxicity or at the subject's request

DRUG

Paclitaxel

Vials, IV, 200 mg/m2, Day 1 of a 21-day cycle, until disease progression, unacceptable toxicity or at the subject's request

DRUG

Carboplatin

Vials, IV, 6 mg/mL.min, Day 1 of a 21-day cycle, until disease progression, unacceptable toxicity or at the subject's request

Trial Locations (5)

3002

Local Institution, East Melbourne

3050

Local Institution, Parville

T6G 1Z2

Local Institution, Edmonton

L8V 5C2

Local Institution, Hamilton

138-736

Local Institution, Seoul

Sponsors
All Listed Sponsors
lead

Bristol-Myers Squibb

INDUSTRY

NCT00793897 - Multiple Dose Study In Cancer Patients: Safety and Tolerability of BMS-754807 in Combination With Paclitaxel and Carboplatin in Patients With Advanced or Metastatic Solid Tumors | Biotech Hunter | Biotech Hunter