NCT00793000 - Safety And Pharmacokinetics Study Of PF-04287881 In Healthy Adults | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

November 30, 2008

Primary Completion Date

December 31, 2009

Study Completion Date

December 31, 2009

Conditions

Respiratory Tract Infections

Interventions

DRUG

PF-04287881

75 mg oral dose (prepared solution) given once

DRUG

Placebo

placebo to match 75 mg oral dose (prepared solution), given once

DRUG

PF-04287881

150 mg oral dose (prepared solution) given once

DRUG

Placebo

placebo to match 150 mg oral dose (prepared solution), given once

DRUG

PF-04287881

300 mg oral dose (prepared solution) given once

DRUG

Placebo

placebo to match 300 mg oral dose (prepared solution), given once

DRUG

PF-04287881

750 mg oral dose (prepared solution) given once

DRUG

Placebo

placebo to match 750 mg oral dose (prepared solution), given once

DRUG

PF-04287881

1000 mg oral dose (prepared solution) given once

DRUG

Placebo

placebo to match 1000 mg oral dose (prepared solution), given once

DRUG

PF-04287881

1250 mg oral dose (prepared solution) given once

DRUG

Placebo

placebo to match 1250 mg oral dose (prepared solution), given once

DRUG

PF-04287881

1500 mg oral dose (prepared solution) given once

DRUG

Placebo

placebo to match 1500 mg oral dose (prepared solution), given once

DRUG

PF-04287881

300 mg oral dose (prepared solution) given once

DRUG

Placebo

placebo to match 300 mg oral dose (prepared solution), given once

DRUG

PF-04287881

750 mg oral dose (prepared solution) given once

DRUG

Placebo

placebo to match 750 mg oral dose (prepared solution), given once

DRUG

PF-04287881

1000 mg based on safety and PK from previous cohorts; oral dose (prepared solution) given once

DRUG

Placebo

placebo to match 1000 mg oral dose (prepared solution), given once

Trial Locations (1)

06511-5473

Pfizer Investigational Site, New Haven