NCT00784277 - A Study to Compare the Frequency of Constipation Symptoms With Tapentadol Immediate Release (IR) Treatment Versus Oxycodone IR Treatment in Patients With End-stage Joint Disease | Biotech Hunter

Enrollment

597

Participants

Timeline

Start Date

October 31, 2008

Primary Completion Date

July 31, 2009

Study Completion Date

July 31, 2009

Conditions

Joint DiseasesArthritisOsteoarthritis

Interventions

DRUG

oxycodone CR

flexible dose tablets and capsules 2 x a day for 28 days (20-60mg/day)

DRUG

oxycodone IR

10mg for 14 days

DRUG

Tapentadol ER (CG5503)

flexible dose tablets and capsules 2 x a day for 28 days (100-500mg/day)

DRUG

Tapentadol IR (CG5503)

50mg for 14 days

DRUG

Tapentadol IR (CG5503)

75mg for 14 days

DRUG

placebo

1 capsule for 14 days

DRUG

placebo

Tablets and capsules 2 x a day for 28 days