A Phase I Clinical Study of Oral CP-4126 in Patients With Advanced Solid Tumour

PHASE1CompletedINTERVENTIONAL
Enrollment

26

Participants

Timeline

Start Date

October 31, 2008

Primary Completion Date

April 30, 2010

Study Completion Date

April 30, 2010

Conditions
Solid Tumors
Interventions
DRUG

CP-4126

Step 1: Dose escalation oral CP-4126 until maximum tolerated dose. Step 2: Oral CP-4126 day 1 and 15 + IV Gemcitabine 1000 mg/m2 day 8 in a 4 week schedule until complete response or disease worsening / progression

DRUG

Gemcitabine

Step 1: Dose escalation oral CP-4126 until maximum tolerated dose Step 2: Oral CP-4126 day 8 and 15 + IV Gemcitabine 1000 mg/m2 day 1 in a 4 week schedule until complete response or disease worsening / progression

Trial Locations (3)

1000

Institute Jules Bordet, Brussels

Unknown

The Netherlands Cancer Institute, Amsterdam

University Medical Centre Utrecht, Utrecht

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Clavis Pharma

INDUSTRY