Comparison of Cy-Atg Vs Cy-Flu-Atg for the Conditioning Therapy in Allo-HCT

PHASE3CompletedINTERVENTIONAL
Enrollment

82

Participants

Timeline

Start Date

March 31, 2003

Primary Completion Date

February 28, 2010

Study Completion Date

January 31, 2011

Conditions
Bone Marrow Failure Syndromes
Interventions
DRUG

Cyclophosphamide-fludarabine-anti thymocyte globulin

"* Cyclophosphamide 50 mg/kg in D5W 200 ml i.v. over 1-2 hours on days -5 to -2 by pump through a central venous catheter.~* Fludarabine 30 mg/m2 will be infused intravenously over 30 minutes in D5W 100 ml for 5 consecutive days (days -6 to -2).~* Thymoglobuline 3 mg/kg in N/S 500-800 mL (less than 0.5 mg/mL) or lymphoglobuline 15 mg/kg in N/S 500-800 mL (less than 2 mg/mL) iv daily at 8 am on days -4 to -2."

Trial Locations (1)

138-736

Asan Medical Center, Seoul

All Listed Sponsors
lead

Cooperative Study Group A for Hematology

NETWORK

NCT00774527 - Comparison of Cy-Atg Vs Cy-Flu-Atg for the Conditioning Therapy in Allo-HCT | Biotech Hunter | Biotech Hunter